Medication module
sertraline
Zoloft · Immediate-release film-coated tablet
Why
Sertraline tablets are immediate-release; they do not appear on the ISMP “Do Not Crush” list and FDA labeling contains no restriction against crushing.
What to ask the pharmacist instead
Ask the pharmacist about the FDA-approved sertraline oral concentrate, which must be diluted as directed in the label before use.
SourceFDA labeling (no crush restriction); not on ISMP “Do Not Crush” list
Clinical review2026-06-10 · pharmacist-checked
Confirm with your pharmacist before changing how any medication is taken. This page never provides dosing guidance.