Medication module
oxycodone extended-release
OxyContin · Extended-release tablet (abuse-deterrent)
Why
Crushing destroys the extended-release mechanism and can release a full day's dose at once — this can be fatal. Never crush, split, chew, or dissolve.
What to ask the pharmacist instead
Ask the prescriber about immediate-release oxycodone liquid or other formulations designed for people who cannot swallow tablets.
SourceISMP “Do Not Crush” list
Clinical review2026-04-02 · pharmacist-checked
Confirm with your pharmacist before changing how any medication is taken. This page never provides dosing guidance.